Wai Yi Leung

Founder of e-Sensei, software and concept development. Occasionally doing consultancy and hardware projects. Wai Yi is a software enthusiast, Python fanatic and D adventurer.

My motto (in Dutch): Software ontwikkeling met focus op realisatie binnen gestelde contraints om stakeholders tegemoet te komen, zonder in te leveren op kwaliteit en onderhoudbaarheid. Ik ambieer een correcte uitvoering, een gulden middenweg is geen oplossing.

Some of my coding is online at Github, some of them on bitbucket. Github profile Bitbucket profile

During my career as a bioinformatician, i've participated in some (in my opinion) interesting research topics. While most of them were validation studies, a couple of projects were really something new in the research field and have not touched before untill we dared to take the challenge unravelling the mythes. Succesfull projects of course, led to writing a paper that gets published. I'll keep adding papers to the list below on the go, not all projects are in the writing phase and most-likely more will follow based on how repetive some will be (My contributions mostly involve in software development and method development).

Title Authors Journal Year of publication
Quaking post-transcriptionally promotes differentiation of monocytes into pro-atherogenic macrophages by controling pre-mRNA splicing and gene expression Ruben de Bruin, Lily Shiue, Jurriën Prins, Hetty de Boer, Anjana Singh, W. Fagg, Janine van Gils, Jacques Duijs, Sol Katzman, Adriaan Kraaijeveld, Stefan Böhringer, Wai Yi Leung, Szymon Kiełbasa, John Donohue, Patrick van der Zande, Rick Sijbom, Carla van Alem, Ilze Bot, Cees van Kooten, J Wouter Jukema, Hilde Van Esch, Ton Rabelink, Hilal Kazan, Erik Biessen, Manuel Ares, Anton Jan van Zonneveld, and Eric van der Veer Nature Communications 2016
The new face of SV detection and tool development for all species SV-AUTOPILOT: Structural Variation AUTOmated PIpeLine Optimization Tool Wai Y. Leung, Tobias Marschall, Yogesh Paudel, Laurent Falquet, Hailang Mei, Alexander Schoenhuth and Tiffanie Yael Maoz BMC Genomics 2015
Complete genome sequence of the Clostridium difficile laboratory strain 630Δerm reveals differences from strain 630, including translocation of the mobile element CTn5 Erika van Eijk, Seyed Yahya Anvar, Hilary P Browne, Wai Yi Leung, Jeroen Frank, Arnoud M Schmitz, Adam P Roberts and Wiep Klaas Smits BMC Genomics 2015
Transactivating mutation of the MYOD1 gene is a frequent event in adult spindle cell rhabdomyosarcoma. Karoly Szuhai,, Daniëlle de Jong, Wai Yi Leung, Christopher DM Fletcher and Pancras CW Hogendoorn The Journal of Pathology 2014
MicroRNA Profiling of Primary Cutaneous Large B-Cell Lymphomas Lianne Koens, Yongjun Qin, Wai Y. Leung, Willem E. Corver, Patty M. Jansen, Rein Willemze, Maarten H. Vermeer, Cornelis P. Tensen PlosOne 2013